Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.69 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700450 | 0.91 | CNR1 (0.68) | CNR1CNR2PTGER4PDE2A | |
| SCHEMBL700628 | 0.88 | CNR1 (0.88) | CNR1CNR2 | |
| SCHEMBL3177198 | 0.87 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL703264 | 0.86 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL702556 | 0.85 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL701648 | 0.85 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL702914 | 0.84 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL700775 | 0.83 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL700577 | 0.82 | CNR1 (0.76) | CNR1CNR2 | |
| SCHEMBL709250 | 0.82 | CNR1 (0.76) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124634-B2 | CB1 receptor modulators | 7TM PHARMA A/S (DK) | 2012-02-28 | — | — | US | claimed |
| US-8124634-B2 | CB1 receptor modulators | 7TM PHARMA A/S (DK) | 2012-02-28 | — | — | US | disclosed |