Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.40 |
| ▸ | WNT3A | P56704 | 6/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31745723 | 0.77 | KDM4E (0.53) | HTR1BCTNNB1WNT3ASLC5A1SLC5A2 | |
| SCHEMBL11097788 | 0.77 | KDM4E (0.53) | HTR1BCTNNB1WNT3ASLC5A1SLC5A2 | |
| SCHEMBL10507927 | 0.76 | HTR1B (0.50) | HTR1BCTNNB1WNT3ATAS1R3TAS1R1 | |
| SCHEMBL13750531 | 0.75 | FFAR1 (0.58) | HTR1BCTNNB1WNT3ACYP1A2 | |
| SCHEMBL13984172 | 0.74 | CYP4F2 (0.54) | HTR1BCTNNB1WNT3ASLC5A1SLC5A2 | |
| SCHEMBL3792011 | 0.74 | HTR1B (0.55) | HTR1BCTNNB1WNT3AEPM2APTPRC | |
| SCHEMBL4521327 | 0.74 | HTR1B (0.50) | HTR1BCTNNB1WNT3AKDM4EMAPT | |
| SCHEMBL28762517 | 0.74 | CYP2C8 (0.50) | HTR1BCTNNB1WNT3ATAS1R3TAS1R1 | |
| SCHEMBL14756106 | 0.73 | HTR1B (0.58) | HTR1BKDM4ELMNATP53CYP1A2 | |
| SCHEMBL7442715 | 0.73 | HTR1B (0.50) | HTR1BCTNNB1WNT3ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | HTR1B 1274/4885CTNNB1 1294/4885WNT3A 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.