SCHEMBL7014417

SCHEMBL7014417

O=C(NCCCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccncc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00
F2 P00734 1/20 0.50
PLAT P00750 1/20 0.50
KLKB1 P03952 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7015165 0.97 F10 (0.95) F10F2PLATKLKB1
SCHEMBL7012456 0.82 F10 (0.70) F10F2PLATKLKB1
SCHEMBL7014175 0.82 F10 (1.00) F10F2PLATKLKB1
SCHEMBL7015552 0.81 F10 (1.00) F10F2PLATKLKB1
SCHEMBL7012622 0.81 F10 (1.00) F10F2PLATKLKB1
SCHEMBL7018231 0.81 F10 (0.79) F10F2PLATKLKB1
SCHEMBL7017078 0.81 F10 (1.00) F10F2PLATKLKB1
SCHEMBL7016206 0.80 F10 (0.86) F10F2PLATKLKB1
SCHEMBL7017411 0.80 F10 (1.00) F10F2PLATKLKB1
SCHEMBL7008213 0.80 F10 (0.85) F10F2PLATKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1302462-A1 SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-04-16 EP disclosed