Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 11/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015252 | 0.88 | GNRHR (0.72) | GNRHR | |
| SCHEMBL7006804 | 0.88 | GNRHR (0.73) | GNRHR | |
| SCHEMBL7015672 | 0.83 | GNRHR (0.81) | GNRHR | |
| SCHEMBL7009390 | 0.78 | GNRHR (0.73) | GNRHR | |
| SCHEMBL7011101 | 0.78 | GNRHR (0.72) | GNRHR | |
| SCHEMBL7012390 | 0.77 | GNRHR (0.71) | GNRHR | |
| SCHEMBL7017601 | 0.77 | GNRHR (0.70) | GNRHR | |
| SCHEMBL7009154 | 0.76 | GNRHR (0.70) | GNRHR | |
| SCHEMBL7007648 | 0.76 | GNRHR (0.93) | GNRHR | |
| SCHEMBL7014303 | 0.75 | GNRHR (0.64) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756599-B1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-11-26 | — | — | EP | claimed |