Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 15/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015723 | 0.95 | NPY1R (0.40) | NPY1RKCNH2SPHK1MAPTNPC1 | |
| SCHEMBL7018244 | 0.95 | NPY1R (0.41) | NPY1RKCNH2SPHK1MAPTNPC1 | |
| SCHEMBL7015321 | 0.93 | NPY1R (0.42) | NPY1RKCNH2SPHK1MAPTSMN1; SMN2 | |
| SCHEMBL7016539 | 0.92 | NPY1R (0.40) | NPY1RKCNH2SPHK1BTK | |
| SCHEMBL7022460 | 0.92 | NPY1R (0.40) | NPY1RKCNH2SPHK1MAPTSMN1; SMN2 | |
| SCHEMBL7013292 | 0.90 | NPY1R (0.48) | NPY1RKCNH2SPHK1BTK | |
| SCHEMBL7019087 | 0.84 | NPY1R (0.40) | NPY1RKCNH2SPHK1BTK | |
| SCHEMBL647566 | 0.84 | NPY1R (0.46) | NPY1R | |
| SCHEMBL7011470 | 0.84 | NPY1R (0.35) | NPY1RKCNH2SPHK1 | |
| SCHEMBL7101967 | 0.81 | NPY1R (0.53) | NPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |