Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 18/20 | 0.54 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012065 | 0.95 | NPY1R (0.53) | NPY1RJAK2JAK1JAK3KCNH2 | |
| SCHEMBL7016590 | 0.94 | NPY1R (0.57) | NPY1RJAK2JAK1JAK3TTK | |
| SCHEMBL8052258 | 0.92 | NPY1R (0.57) | NPY1RKCNH2 | |
| SCHEMBL7011579 | 0.90 | NPY1R (0.66) | NPY1RKCNH2 | |
| SCHEMBL647566 | 0.90 | NPY1R (0.46) | NPY1RJAK2JAK1JAK3TTK | |
| SCHEMBL7017313 | 0.90 | NPY1R (0.55) | NPY1RKCNH2 | |
| SCHEMBL7015274 | 0.90 | NPY1R (0.46) | NPY1RJAK2JAK1JAK3TTK | |
| SCHEMBL7019780 | 0.90 | NPY1R (0.45) | NPY1RJAK2JAK1JAK3TTK | |
| SCHEMBL7015208 | 0.89 | NPY1R (0.67) | NPY1RKCNH2 | |
| SCHEMBL8057456 | 0.89 | NPY1R (0.49) | NPY1RJAK2JAK1JAK3TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |