Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654641 | 0.89 | CREBBP (0.49) | CREBBPGAAMAPTTP53TRPA1 | |
| SCHEMBL6651475 | 0.85 | CREBBP (0.40) | CREBBPGAAMAPTALOX5TP53 | |
| SCHEMBL7011739 | 0.82 | GAA (0.52) | CREBBPGAAMAPTTP53ATM | |
| SCHEMBL5168350 | 0.78 | CREBBP (0.66) | CREBBPGAAMAPTTP53TRPA1 | |
| SCHEMBL6651479 | 0.77 | CREBBP (0.57) | CREBBPGAAMAPTTP53TRPA1 | |
| SCHEMBL5166516 | 0.74 | MAPT (0.61) | GAAMAPTTP53 | |
| SCHEMBL5169227 | 0.73 | CREBBP (0.56) | CREBBPGAAMAPTTP53 | |
| SCHEMBL6649635 | 0.72 | GAA (0.60) | GAAMAPTTP53TRPA1ADRA1B | |
| SCHEMBL7015470 | 0.72 | MAPT (0.48) | GAAMAPTTP53TRPA1ADRA1B | |
| SCHEMBL5166815 | 0.72 | MAPT (0.48) | CREBBPGAAMAPTTP53ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218378-B1 | TERT.-BUTYL-(7-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-YL)-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2003-04-23 | — | — | EP | claimed |