Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28288866 | 0.84 | HTR2A (0.46) | HTR2AMPOTRPM8PSEN1PSEN2 | |
| SCHEMBL2808716 | 0.80 | KDM4E (0.41) | HTR2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29899701 | 0.75 | AKR1B1 (0.46) | TRPV4 | |
| SCHEMBL113810 | 0.75 | AKR1B1 (0.46) | TRPV4 | |
| SCHEMBL13739523 | 0.75 | TSHR (0.45) | — | |
| Hydrochloric Acid SCHEMBL7003803 | 0.74 | AKR1B1 (0.45) | TRPV4 | |
| SCHEMBL441642 | 0.73 | TAAR1 (0.54) | HTR2AMPOTRPM8PSEN1PSEN2 | |
| SCHEMBL14991466 | 0.72 | PSEN1 (0.39) | HTR2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31504506 | 0.72 | TAAR1 (0.52) | HTR2AMPOTRPM8PSEN1PSEN2 | |
| SCHEMBL13692282 | 0.72 | TAAR1 (0.52) | HTR2AMPOTRPM8PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124722-B2 | quantitatively or qualitatively determine human low molecular weight CD14 with high sensitivity and specificity in a simple manner | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-7608684-B2 | Soluble CD14 antigen | MOCHIDA PHARMACEUTICALS CO., LTD. (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20090203052-A1 | NOVEL SOLUBLE CD14 ANTIGEN | FURUSAKO SHOJI | 2009-08-13 | — | — | US | disclosed |
| US-20060068445-A1 | Novel soluble CD14 antigen | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |