Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775785 | 0.86 | TET2 (0.48) | TET2TET1TNFMAPTLMNA | |
| SCHEMBL31369561 | 0.82 | MAPT (0.66) | TNFMAPTKMT2ALMNAKDM4E | |
| SCHEMBL26377272 | 0.78 | CYP1A2 (0.48) | KDM4EALDH1A1ADORA3HSD17B10NLN | |
| SCHEMBL31641352 | 0.77 | KMT2A (0.62) | TNFMAPTKMT2ALMNAKDM4E | |
| SCHEMBL31642354 | 0.77 | KMT2A (0.62) | TNFMAPTKMT2ALMNAKDM4E | |
| SCHEMBL7277532 | 0.77 | KMT2A (0.62) | TNFMAPTKMT2ALMNAKDM4E | |
| SCHEMBL29406016 | 0.77 | KMT2A (0.62) | TNFMAPTKMT2ALMNAKDM4E | |
| SCHEMBL5298198 | 0.77 | KMT2A (0.62) | TNFMAPTKMT2ALMNAKDM4E | |
| SCHEMBL1520374 | 0.77 | KMT2A (0.62) | TNFMAPTKMT2ALMNAKDM4E | |
| SCHEMBL30759412 | 0.77 | KMT2A (0.62) | TNFMAPTKMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255757-B1 | AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2003-06-18 | — | — | EP | disclosed |