SCHEMBL701701

SCHEMBL701701

N#CCc1c(C(=O)O)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10087251 0.89 CNR1 (0.65) CNR1
SCHEMBL4633715 0.89 CNR1 (0.63) CNR1
Hydrochloric Acid SCHEMBL8018664 0.88 CNR1 (0.62) CNR1
SCHEMBL4634228 0.88 CNR1 (0.69) CNR1
SCHEMBL2679126 0.85 CNR1 (0.65) CNR1
SCHEMBL14161984 0.84 CNR1 (0.59) CNR1
SCHEMBL2063699 0.84 CNR1 (1.00) CNR1
SCHEMBL27646546 0.83 CNR1 (0.55) CNR1
SCHEMBL3821972 0.83 CNR1 (0.69) CNR1
SCHEMBL14214779 0.82 CNR1 (1.00) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121617-B1 CB1 RECEPTOR MODULATORS 7TM PHARMA AS (DK) 2014-01-22 EP disclosed
EP-2121617-B1 CB1 RECEPTOR MODULATORS 7TM PHARMA AS (DK) 2014-01-22 EP disclosed
EP-2121659-B1 MODULATORS OF CB1 RECEPTORS 7TM PHARMA AS (DK) 2013-05-15 EP disclosed
EP-2121659-B1 MODULATORS OF CB1 RECEPTORS 7TM PHARMA AS (DK) 2013-05-15 EP disclosed
US-8173680-B2 Cannabinoid receptor modulators 7TM PHARMA A/S (DK) 2012-05-08 US disclosed
US-8173680-B2 Cannabinoid receptor modulators 7TM PHARMA A/S (DK) 2012-05-08 US disclosed
US-8148404-B2 Modulators of CB1 receptors 7TM PHARMA A/S (DK) 2012-04-03 US disclosed
US-8148404-B2 Modulators of CB1 receptors 7TM PHARMA A/S (DK) 2012-04-03 US disclosed
US-8148404-B2 Modulators of CB1 receptors 7TM PHARMA A/S (DK) 2012-04-03 US disclosed
US-8124634-B2 CB1 receptor modulators 7TM PHARMA A/S (DK) 2012-02-28 US disclosed
EP-2094666-A1 CANNABINOID RECEPTOR MODULATORS 7TM Pharma A/S (DK) 2009-09-02 EP disclosed
WO-2009074782-A1 CANNABINOID RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2009-06-18 WO disclosed
WO-2009074782-A1 CANNABINOID RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2009-06-18 WO disclosed
US-20080200527-A1 Cannabinoid Receptor Modulators CAREX SA (FR) 2008-08-21 US disclosed
WO-2008075012-A1 CB1 RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2008-06-26 WO disclosed
WO-2008075013-A1 MODULATORS OF CANNABINOID RECEPTOR 7TM PHARMA A/S (DK) 2008-06-26 WO disclosed
WO-2008075019-A1 MODULATORS OF CB1 RECEPTORS 7TM PHARMA A/S (DK) 2008-06-26 WO disclosed
EP-1928859-A1 PYRAZOLE DERIVATES AS CANNABINOID RECEPTOR MODULATORS Carex SA (FR) 2008-06-11 EP disclosed
WO-2008059207-A1 CANNABINOID RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2008-05-22 WO disclosed
WO-2006133926-A1 PYRAZOLE DERIVATES AS CANNABINOID RECEPTOR MODULATORS CAREX SA (FR) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200527-A1 Cannabinoid Receptor Modulators CNR1, CNR2, HCRTR2 CNR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.