Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 20/20 | 0.68 |
| ▸ | MME | P08473 | 1/20 | 0.65 |
| ▸ | ACE | P12821 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016780 | 0.93 | ECE1 (0.79) | ECE1MMEACE | |
| SCHEMBL6773725 | 0.93 | ECE1 (0.59) | ECE1MMEACE | |
| SCHEMBL7020651 | 0.91 | ECE1 (0.79) | ECE1MMEACE | |
| SCHEMBL7017535 | 0.91 | ECE1 (0.77) | ECE1 | |
| SCHEMBL7013046 | 0.90 | ECE1 (0.82) | ECE1MMEACE | |
| SCHEMBL7019562 | 0.90 | ECE1 (0.82) | ECE1MMEACE | |
| SCHEMBL7020754 | 0.90 | ECE1 (0.81) | ECE1MMEACE | |
| SCHEMBL7016773 | 0.89 | ECE1 (0.80) | ECE1MMEACE | |
| SCHEMBL7017124 | 0.88 | ECE1 (0.81) | ECE1MMEACE | |
| SCHEMBL6777654 | 0.88 | ECE1 (0.86) | ECE1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255757-B1 | AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2003-06-18 | — | — | EP | disclosed |