Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.33 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | MELK | Q14680 | 4/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021290 | 0.68 | SCN4A (0.54) | SCN4APARP1PFKFB2PFKFB1PFKFB3 | |
| SCHEMBL18580371 | 0.68 | SCN4A (0.65) | SCN4APFKFB2PFKFB1PFKFB3ELANE | |
| SCHEMBL16635510 | 0.68 | SCN4A (0.53) | SCN4APFKFB2PFKFB1PFKFB3ELANE | |
| SCHEMBL4772053 | 0.66 | SCN4A (0.43) | SCN4APARP1DHODHPFKFB2PFKFB1 | |
| Hydrochloric Acid SCHEMBL7399583 | 0.65 | SCN4A (0.60) | SCN4APFKFB2PFKFB1PFKFB3GLI1 | |
| SCHEMBL255493 | 0.64 | GLI1 (0.66) | SCN4AGLI1 | |
| SCHEMBL894617 | 0.64 | GLI1 (0.66) | SCN4AGLI1 | |
| SCHEMBL490079 | 0.64 | GLI1 (0.66) | SCN4AGLI1 | |
| Proline SCHEMBL27493189 | 0.64 | SCN4A (0.46) | SCN4AGLI1 | |
| Proline SCHEMBL28198776 | 0.64 | SCN4A (0.46) | SCN4AGLI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309565-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | claimed |
| WO-2002012199-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-14 | — | — | WO | claimed |
| EP-1309565-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012199-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-14 | — | — | WO | disclosed |