Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407219 | 0.89 | ELANE (0.67) | ELANE | |
| SCHEMBL7278015 | 0.88 | ELANE (0.67) | ELANE | |
| SCHEMBL7007242 | 0.85 | ELANE (0.55) | ELANE | |
| SCHEMBL7281341 | 0.83 | ELANE (0.64) | ELANE | |
| SCHEMBL7387523 | 0.83 | ELANE (0.48) | ELANE | |
| SCHEMBL7290427 | 0.82 | ELANE (0.64) | ELANE | |
| SCHEMBL7278147 | 0.82 | ELANE (0.69) | ELANE | |
| SCHEMBL7291592 | 0.82 | ELANE (0.57) | ELANE | |
| SCHEMBL8521554 | 0.81 | ELANE (0.60) | ELANE | |
| SCHEMBL7303741 | 0.81 | ELANE (0.58) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547708-B1 | Saccharin derivative proteolytic enzyme inhibitors | SANOFI SYNTHELABO (FR) | 2003-02-26 | — | — | EP | disclosed |
| US-5466701-A | Degenerative diseases | STERLING WINTHROP INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5378720-A | Treatment of rheumatoid arthritis, emphysema, pancreatitis | STERLING WINTHROP INC. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0626378-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-11-30 | — | — | EP | disclosed |
| EP-0547708-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-06-23 | — | — | EP | disclosed |