Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 6/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527505 | 0.86 | ACE (0.47) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL7026299 | 0.85 | ATM (0.46) | ATMSYKCTSSCTSKCTSL | |
| SCHEMBL7020848 | 0.84 | ATM (0.45) | ATMSYKCTSSCTSKCTSL | |
| SCHEMBL7016941 | 0.83 | ATM (0.46) | ATMSYKCTSSCTSKCTSL | |
| SCHEMBL7018122 | 0.83 | ATM (0.46) | ATMSYKCTSSCTSKCTSL | |
| SCHEMBL7020336 | 0.81 | ATM (0.42) | ATMCTSSCTSKSCN9A | |
| SCHEMBL7464877 | 0.81 | ATM (0.47) | ATMSYKCTSSCTSKCTSL | |
| SCHEMBL7464875 | 0.81 | ATM (0.47) | ATMSYKCTSSCTSKCTSL | |
| SCHEMBL7021557 | 0.81 | PTPN1 (0.44) | ATMSYKCTSK | |
| SCHEMBL7021561 | 0.81 | PTPN1 (0.44) | ATMSYKCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149076-B1 | O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME | SK CORP (KR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1149076-A1 | O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME | SK Corporation (KR) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000046191-A1 | O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME | SK CORPORATION (KR) | 2000-08-10 | — | — | WO | disclosed |
| US-5935997-A | O-thiocarbamoyl-aminoalkanol compounds, their pharmaceutically useful salts and process for preparing the same | YUKONG LIMITED (KR) | 1999-08-10 | — | — | US | disclosed |