Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.34 |
| ▸ | KDR | P35968 | 7/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101964 | 0.88 | NPY1R (0.38) | NPY1RFGFR1KDREPHB4KCNH2 | |
| SCHEMBL7012016 | 0.86 | NPY1R (0.35) | NPY1RKCNH2 | |
| SCHEMBL7018659 | 0.85 | NPY1R (0.48) | NPY1RKCNH2 | |
| SCHEMBL7101967 | 0.81 | NPY1R (0.53) | NPY1RKCNH2 | |
| SCHEMBL7019088 | 0.79 | NPY1R (0.48) | NPY1RKCNH2 | |
| SCHEMBL7012020 | 0.79 | NPY1R (0.45) | NPY1RKCNH2 | |
| SCHEMBL7018031 | 0.78 | TSHR (0.35) | NPY1RKCNH2 | |
| SCHEMBL7022451 | 0.78 | NPY1R (0.36) | NPY1RKCNH2 | |
| SCHEMBL647566 | 0.78 | NPY1R (0.46) | NPY1R | |
| SCHEMBL7021884 | 0.77 | AKT1 (0.35) | NPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |