Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355693 | 0.92 | SMN1; SMN2 (0.58) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL14810258 | 0.87 | CHRM1 (0.76) | CHRM1CHRM2SMN1; SMN2TP53TDP1 | |
| Isonipecotic Acid SCHEMBL7473381 | 0.84 | SMN1; SMN2 (0.50) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL28253726 | 0.83 | SMN1; SMN2 (0.51) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL14159621 | 0.83 | SMN1; SMN2 (0.51) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL2345851 | 0.83 | SMN1; SMN2 (0.51) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL4474676 | 0.83 | CHRM1 (0.51) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL11578382 | 0.82 | GAA (0.56) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL3310701 | 0.82 | SMN1; SMN2 (0.51) | CHRM1CHRM2SMN1; SMN2LMNAPOLB | |
| SCHEMBL14964905 | 0.82 | CHRM1 (0.68) | CHRM1CHRM2SMN1; SMN2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | CHRM1 1840/4885CHRM2 1953/4885SMN1; SMN2 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.