Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.56 |
| ▸ | GSK3A | P49840 | 4/20 | 0.56 |
| ▸ | CDK1 | P06493 | 3/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394516 | 0.85 | GSK3B (0.76) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7858290 | 0.83 | GSK3B (0.59) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5094214 | 0.83 | GSK3B (0.59) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4401819 | 0.83 | GSK3B (0.61) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5094253 | 0.83 | GSK3B (0.59) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7014382 | 0.79 | GSK3B (0.53) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7248860 | 0.77 | GSK3B (0.59) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5100682 | 0.77 | GSK3B (0.64) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4404414 | 0.77 | GSK3B (0.55) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7248826 | 0.76 | GSK3B (0.60) | GSK3BGSK3ACDK1CCNB2CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |