Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 15/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 14/20 | 0.51 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019987 | 0.85 | PDE4A (0.53) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL7017226 | 0.85 | AVPR1A (0.45) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7020818 | 0.84 | MAPT (0.43) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7015488 | 0.84 | AVPR1A (0.50) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7016285 | 0.84 | AVPR1A (0.44) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7020700 | 0.84 | AVPR1A (0.40) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7017240 | 0.83 | PDE4A (0.50) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL7025547 | 0.83 | AVPR1A (0.39) | AVPR2AVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7018912 | 0.83 | AVPR1A (0.44) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7024187 | 0.82 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051415-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6495542-B1 | SUCH AS 2-METHOXY-N-(2-METHYL-1H-BENZIMIDAZOL-4-YL)-4-(2,3,4,5-TETRAHYDRO-5-OXO-1H-1-BENZAZEPIN-1-YL)CARBONYL-BENZAM IDE; HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |