Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024690 | 0.86 | SCN9A (0.52) | F10SCN9ACA1CA2CA12 | |
| SCHEMBL7027098 | 0.85 | SCN9A (0.51) | F10SCN9AMMP3 | |
| SCHEMBL7106774 | 0.84 | SCN9A (0.50) | F10SCN9ACA1CA2MMP3 | |
| SCHEMBL7027060 | 0.84 | MEN1 (0.62) | F10SCN9ACA1CA2CA12 | |
| SCHEMBL7025531 | 0.83 | HPGD (0.53) | F10SCN9ACA1CA2CA12 | |
| SCHEMBL7030338 | 0.83 | CA12 (0.67) | SCN9ACA1CA2CA12CA5A | |
| SCHEMBL7025057 | 0.82 | SCN9A (0.52) | F10SCN9ACA2 | |
| SCHEMBL7024709 | 0.82 | F10 (0.48) | F10SCN9AMMP3 | |
| SCHEMBL7027503 | 0.82 | HPGD (0.54) | F10SCN9ACA1CA2MMP3 | |
| SCHEMBL7029507 | 0.81 | TRPV1 (0.51) | F10SCN9ACA1CA2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309549-A1 | ACETAMIDE DERIVATIVES AND THE USE THEREOF AS INHIBITORS OF COAGULATION FACTORS XA AND VIIA | MERCK PATENT GmbH (DE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002010127-A1 | ACETAMIDE DERIVATIVES AND THE USE THEREOF AS INHIBITORS OF COAGULATION FACTORS XA AND VIIA | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | WO | disclosed |