Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020603 | 1.00 | ELANE (0.38) | ELANEALDH1A1HTR2CPSEN1PSEN2 | |
| SCHEMBL6151882 | 0.82 | ELANE (0.35) | ELANEALDH1A1 | |
| SCHEMBL6151883 | 0.82 | ELANE (0.35) | ELANEALDH1A1 | |
| SCHEMBL6860240 | 0.81 | ELANE (0.47) | ELANEALDH1A1HTR2CHTTPDE1C | |
| SCHEMBL6860243 | 0.81 | ELANE (0.47) | ELANEALDH1A1HTR2CHTTPDE1C | |
| SCHEMBL6150759 | 0.78 | ELANE (0.31) | ELANE | |
| SCHEMBL6150760 | 0.78 | ELANE (0.31) | ELANE | |
| SCHEMBL30904956 | 0.65 | ELANE (0.43) | ELANEHTR2CPDE1C | |
| SCHEMBL12571331 | 0.65 | HTR2C (0.48) | ELANEALDH1A1HTR2CPSEN1PSEN2 | |
| SCHEMBL23744030 | 0.65 | HTR2C (0.45) | ELANEALDH1A1HTR2CPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668762-B1 | ISOBUTENYL-SUBSTITUTED TAXANES AND THEIR PHARMACEUTICAL COMPOSITIONS | UNIV FLORIDA STATE (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6005138-A | ANTILEUKEMIA AND ANTITUMOR AGENTS | FLORIDA STATE UNIVERSITY (US) | 1999-12-21 | — | — | US | disclosed |