Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 19/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDE6C | P51160 | 1/20 | 0.46 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314197 | 0.79 | PDE5A (0.54) | PDE5AMAPT | |
| SCHEMBL6314283 | 0.79 | PDE5A (0.53) | PDE5AMAPTPDE6CPDE11A | |
| SCHEMBL6305495 | 0.78 | PDE5A (0.59) | PDE5AMAPTPDE6C | |
| SCHEMBL6305699 | 0.74 | PDE5A (0.51) | PDE5AMAPTPDE6CPDE11A | |
| SCHEMBL5827475 | 0.73 | PDE5A (0.75) | PDE5APDE6CPDE11A | |
| SCHEMBL6304667 | 0.73 | PDE5A (0.61) | PDE5A | |
| SCHEMBL6312475 | 0.73 | PDE5A (0.60) | PDE5A | |
| SCHEMBL5827397 | 0.71 | PDE5A (0.59) | PDE5A | |
| SCHEMBL5827936 | 0.70 | PDE5A (0.57) | PDE5A | |
| SCHEMBL6313641 | 0.70 | PDE5A (0.56) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286997-A1 | 6-PHENYLPYRROLOPYRIMIDINEDIONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094350-A1 | 6-PHENYLPYRROLOPYRIMIDINEDIONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2001-12-13 | — | — | WO | disclosed |