Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021980 | 0.90 | F2 (0.62) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7024780 | 0.89 | F2 (0.62) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7022679 | 0.88 | F2 (0.46) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7019802 | 0.86 | F2 (0.63) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7025567 | 0.85 | F2 (0.62) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7026174 | 0.84 | F2 (0.60) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7992846 | 0.84 | F2 (0.60) | F2PRSS1PRSS2PRSS3MASP2 | |
| Hydrochloric Acid SCHEMBL7026964 | 0.78 | F2 (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7020324 | 0.78 | F2 (0.47) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7023456 | 0.78 | F2 (0.47) | F2PRSS1PRSS2PRSS3MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |