SCHEMBL70220

SCHEMBL70220

COC(=O)c1ccccc1/N=N/c1ccccc1C(=O)OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.65
THRB P10828 1/20 0.65
NPSR1 Q6W5P4 2/20 0.63
ALDH1A1 P00352 3/20 0.61
GAA P10253 2/20 0.61
GFER P55789 1/20 0.61
TSHR P16473 3/20 0.59
LMNA P02545 2/20 0.59
HSD17B10 Q99714 2/20 0.57
KDM4E B2RXH2 2/20 0.57
HPGD P15428 2/20 0.57
CFTR P13569 1/20 0.57
ATM Q13315 2/20 0.55
POLB P06746 1/20 0.55
KMT2A Q03164 4/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70221 1.00 MAPT (0.65) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL29021505 0.91 MAPT (0.62) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL28098512 0.91 MAPT (0.62) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL1505880 0.88 TSHR (0.59) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL11349080 0.86 TSHR (0.57) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL29021512 0.85 MAPT (0.52) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL28659830 0.84 TSHR (0.55) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL21189801 0.84 TSHR (0.55) MAPTTHRBNPSR1ALDH1A1GAA
SCHEMBL922165 0.82 TSHR (0.53) MAPTTHRBNPSR1ALDH1A1GAA
Dimethyl Phthalate SCHEMBL34630 0.82 TSHR (0.74) MAPTALDH1A1TSHRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885THRB 2913/4885NPSR1 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.