⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674812 | 0.90 | — | — | |
| SCHEMBL8399906 | 0.84 | USP2 (0.33) | — | |
| SCHEMBL17965740 | 0.82 | USP2 (0.39) | — | |
| SCHEMBL17965697 | 0.80 | USP2 (0.42) | — | |
| SCHEMBL17965721 | 0.80 | USP2 (0.42) | — | |
| SCHEMBL17965715 | 0.80 | USP2 (0.42) | — | |
| SCHEMBL17965735 | 0.80 | USP2 (0.42) | — | |
| SCHEMBL11050307 | 0.80 | USP2 (0.42) | — | |
| SCHEMBL8378655 | 0.76 | — | — | |
| SCHEMBL1452729 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509003-B2 | N-alkylpiperidine derivatives labeled with radioactive iodine; use in single photon emission computed tomography (SPECT) | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-0989120-B1 | REAGENTS FOR ASSAYING CENTRAL LOCAL ACETYLCHOLINESTERASE ACTIVITY | DAIICHI PURE CHEMICALS CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-20020127180-A1 | Reagents for the determination of cerebral regional acetylcholinesterase activity | DAIICHI PURE CHEMICALS CO., LTD (JP) | 2002-09-12 | — | — | US | disclosed |
| US-6306882-B1 | FLUOROALKYLPIPERIDINE ESTERS COGNITION ACTIVATORS AND ALZHEIMER'S | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-0989120-A1 | REAGENTS FOR ASSAYING CENTRAL LOCAL ACETYLCHOLINESTERASE ACTIVITY | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0173395-B1 | PERFUME COMPOSITIONS AND PERFUMED PRODUCTS WHICH CONTAIN ONE OR MORE 4,7-ALKADIENALS AS THE ESSENTIAL SUBSTANCE | NAARDEN INTERNATIONAL N.V. (NL) | 1988-12-28 | — | — | EP | disclosed |
| US-4687599-A | Perfume compositions and perfumed products which contain one or more 4,7-alkadienals as the essential substance | NAARDEN INTERNATIONAL N.V. (NL) | 1987-08-18 | — | — | US | disclosed |
| EP-0173395-A1 | Perfume compositions and perfumed products which contain one or more 4,7-alkadienals as the essential substance | NAARDEN INTERNATIONAL N.V. (NL) | 1986-03-05 | — | — | EP | disclosed |
| US-4189431-A | CYCLIZATION OF POLYENINE TO POLYCYCLIC COMPOUND HAVING CYCLOPENTANO RING | The Board of Trustees of Leland Stanford Junior University (US) | 1980-02-19 | — | — | US | disclosed |
| US-4055603-A | HORMONES | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 1977-10-25 | — | — | US | disclosed |