Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22187247 | 0.90 | NPC1 (0.51) | LMNASMN1; SMN2POLBL3MBTL1MAPT | |
| SCHEMBL22187139 | 0.87 | NPC1 (0.49) | LMNASMN1; SMN2POLBL3MBTL1MAPT | |
| SCHEMBL22187149 | 0.81 | POLB (0.47) | BRD4LMNASMN1; SMN2TSHRPOLB | |
| SCHEMBL30579823 | 0.81 | POLB (0.47) | BRD4LMNASMN1; SMN2TSHRPOLB | |
| SCHEMBL22187253 | 0.81 | CYP1A2 (0.51) | LMNASMN1; SMN2POLBL3MBTL1MAPT | |
| SCHEMBL27081686 | 0.80 | CA12 (0.63) | LMNASMN1; SMN2L3MBTL1KDM4EMAPT | |
| SCHEMBL22187250 | 0.80 | CYP1A2 (0.50) | LMNASMN1; SMN2POLBL3MBTL1MAPT | |
| SCHEMBL29564249 | 0.80 | BRD4 (0.54) | HSD17B10BRD4LMNASMN1; SMN2TSHR | |
| SCHEMBL10338947 | 0.80 | BRD4 (0.54) | HSD17B10BRD4LMNASMN1; SMN2TSHR | |
| SCHEMBL29673500 | 0.79 | KMT2A (0.52) | MAPK1LMNAPOLBL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051393-B1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | MERCK SANTE SAS (FR) | 2003-10-01 | — | — | EP | claimed |