Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544392 | 0.94 | HTT (0.33) | CHRM5ADRA2CGBA1HTTNCF1 | |
| SCHEMBL7026183 | 0.94 | HTT (0.33) | CHRM5ADRA2CGBA1HTTNCF1 | |
| SCHEMBL3934463 | 0.94 | HTT (0.33) | CHRM5ADRA2CGBA1HTTNCF1 | |
| SCHEMBL11537690 | 0.92 | CHRM5 (0.40) | CHRM5ADRA2CGBA1HTTACHE | |
| SCHEMBL10563375 | 0.92 | CHRM5 (0.40) | CHRM5ADRA2CGBA1HTTACHE | |
| SCHEMBL4586403 | 0.90 | CHRM5 (0.43) | CHRM5ADRA2CGBA1ACHECHRM2 | |
| SCHEMBL3504249 | 0.90 | CHRM5 (0.43) | CHRM5ADRA2CGBA1ACHECHRM2 | |
| SCHEMBL10722386 | 0.90 | CHRM5 (0.43) | CHRM5ADRA2CGBA1ACHECHRM2 | |
| SCHEMBL28774451 | 0.80 | HTT (0.35) | CHRM5ADRA2CHTTNCF1 | |
| SCHEMBL10686512 | 0.79 | CHRM5 (0.40) | CHRM5ADRA2CGBA1ACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |