Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513087 | 0.76 | — | — | |
| SCHEMBL6889643 | 0.75 | TSHR (0.40) | ALDH1A1TSHRMAPK1SLC7A5ANPEP | |
| SCHEMBL6720278 | 0.69 | TSHR (0.40) | ALDH1A1TSHRMAPK1SLC7A5ANPEP | |
| SCHEMBL19879326 | 0.69 | TSHR (0.40) | ALDH1A1TSHRMAPK1SLC7A5ANPEP | |
| SCHEMBL42768 | 0.67 | — | — | |
| SCHEMBL223978 | 0.67 | TSHR (0.45) | ALDH1A1TSHRMAPK1SLC7A5ANPEP | |
| SCHEMBL6720279 | 0.67 | SLC7A5 (0.40) | ALDH1A1TSHRMAPK1SLC7A5ANPEP | |
| SCHEMBL223977 | 0.67 | TSHR (0.38) | ALDH1A1TSHRMAPK1SLC7A5ANPEP | |
| SCHEMBL6893519 | 0.67 | TSHR (0.38) | ALDH1A1TSHRMAPK1SLC7A5ANPEP | |
| SCHEMBL26212033 | 0.67 | TSHR (0.45) | ALDH1A1TSHRMAPK1SLC7A5ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |