Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295592 | 0.90 | SYK (0.59) | SYKMAPTSMN1; SMN2LMNAIDO1 | |
| SCHEMBL7910002 | 0.88 | SYK (0.70) | SYKMAPTSMN1; SMN2LMNAIDO1 | |
| SCHEMBL7026898 | 0.88 | SYK (0.70) | SYKMAPTSMN1; SMN2LMNAIDO1 | |
| SCHEMBL30500935 | 0.88 | SYK (0.70) | SYKMAPTSMN1; SMN2LMNAIDO1 | |
| SCHEMBL19972926 | 0.85 | SYK (0.64) | SYKMAPTSMN1; SMN2LMNAIDO1 | |
| SCHEMBL15202883 | 0.85 | SYK (0.64) | SYKMAPTSMN1; SMN2LMNAIDO1 | |
| SCHEMBL31236564 | 0.85 | SYK (0.65) | SYKMAPTSMN1; SMN2LMNAIDO1 | |
| SCHEMBL1627707 | 0.84 | SYK (0.67) | SYKMAPTIDO1CTSSPPARA | |
| SCHEMBL6312567 | 0.83 | SYK (0.74) | SYKMAPTCTSSPPARACTSK | |
| SCHEMBL3911383 | 0.83 | SYK (0.67) | SYKMAPTSMN1; SMN2LMNACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330436-A1 | N-(4-ARYLOXYPIPERIDIN-1-YLALKYL) CINNAMIC AMIDES AS CCR3-3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002030898-A1 | N-(4-ARYLOXYPIPERIDIN-1-YLALKYL) CINNAMIC AMIDES AS CCR33 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2002-04-18 | — | — | WO | disclosed |