Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.52 |
| ▸ | ITGAL | P20701 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423072 | 0.76 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL5436015 | 0.76 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL17295109 | 0.75 | IDO1 (0.35) | — | |
| SCHEMBL14561974 | 0.75 | ITGB2 (0.50) | ITGB2ICAM1ITGAL | |
| SCHEMBL14572510 | 0.72 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL14562022 | 0.72 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL5453672 | 0.71 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL7025684 | 0.71 | ITGB2 (0.81) | ITGB2ICAM1ITGAL | |
| SCHEMBL7021938 | 0.70 | ITGB2 (0.44) | ITGB2ICAM1ITGAL | |
| SCHEMBL5436135 | 0.70 | ITGB2 (0.53) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294704-A1 | ARYL PHENYLHETEROCYCLYL SULFIDE DERIVATIVES AND THEIR USE AS CELL ADHESION-INHIBITING ANTI-INFLAMMATORY AND IMMUNE-SUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002002539-A1 | ARYL PHENYLHETEROCYCLYL SULFIDE DERIVATIVES AND THEIR USE AS CELL ADHESION-INHIBITING ANTI-INFLAMMATORY AND IMMUNE-SUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 2002-01-10 | — | — | WO | disclosed |