SCHEMBL7023645

SCHEMBL7023645

O=C(CC1C2C=CC(C2)C1C(=O)O)OC(=O)CC1C2C=CC(C2)C1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 5/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ TDP1 Q9NUW8 4/20 0.41
▸ APEX1 P27695 2/20 0.41
▸ LMNA P02545 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.37
▸ TAAR1 Q96RJ0 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ CASP6 P55212 1/20 0.35
▸ HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13346663 0.83 POLB (0.45) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL6308224 0.77 POLB (0.46) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL6308227 0.77 POLB (0.46) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL351244 0.76 POLB (0.47) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL23287488 0.73 POLB (0.70) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL14469601 0.73 POLB (0.70) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL59471 0.73 POLB (0.70) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL5641704 0.73 POLB (0.70) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL1462188 0.73 POLB (0.70) POLBALDH1A1SMN1; SMN2TDP1APEX1
SCHEMBL24062391 0.73 POLB (0.70) POLBALDH1A1SMN1; SMN2TDP1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0967522-B1 Positive photosensitive resin composition FUJI PHOTO FILM CO LTD (JP) 2003-02-19 — — EP disclosed
US-6159656-A Positive photosensitive resin FUJI PHOTO FILM CO., LTD. (JP) 2000-12-12 — — US disclosed
EP-0967522-A1 Positive photosensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1999-12-29 — — EP disclosed
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