Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.65 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.56 |
| ▸ | WNT3A | P56704 | 4/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13314553 | 0.87 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8532983 | 0.85 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL1222503 | 0.85 | HDAC1 (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL10272693 | 0.84 | HDAC1 (0.63) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL13295906 | 0.84 | HDAC1 (0.60) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL12821432 | 0.82 | HDAC2 (0.58) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL20616724 | 0.81 | ESR1 (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8532136 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7218629 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9479087 | 0.81 | HDAC1 (0.70) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397360-A1 | AZAINDOLES | Aventis Pharma Limited (GB) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003000688-A1 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2003-01-03 | — | — | WO | disclosed |