Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 6/20 | 0.31 |
| ▸ | DRD1 | P21728 | 6/20 | 0.31 |
| ▸ | DRD4 | P21917 | 6/20 | 0.31 |
| ▸ | DRD5 | P21918 | 6/20 | 0.31 |
| ▸ | DRD3 | P35462 | 6/20 | 0.31 |
| ▸ | DRD2 | P14416 | 5/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387917 | 1.00 | KDM5A (0.33) | KDM5AKDM4CKDM5BHTR1ADRD1 | |
| SCHEMBL7026494 | 0.97 | KDM5A (0.34) | KDM5AKDM4CKDM5B | |
| SCHEMBL8387231 | 0.97 | KDM5A (0.34) | KDM5AKDM4CKDM5B | |
| SCHEMBL7029800 | 0.93 | KDM5A (0.35) | KDM5AKDM4CKDM5BDRD2 | |
| SCHEMBL8389631 | 0.93 | KDM5A (0.35) | KDM5AKDM4CKDM5BDRD2 | |
| SCHEMBL7024037 | 0.92 | KDM5A (0.33) | KDM5AKDM4CKDM5B | |
| SCHEMBL8387265 | 0.92 | KDM5A (0.33) | KDM5AKDM4CKDM5B | |
| SCHEMBL10502110 | 0.90 | CTSC (0.33) | KDM5AKDM4CKDM5BSPHK1S1PR1 | |
| SCHEMBL10502117 | 0.90 | CTSC (0.33) | KDM5AKDM4CKDM5BSPHK1S1PR1 | |
| SCHEMBL10501474 | 0.89 | SPHK1 (0.36) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |