Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027181 | 1.00 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL7024183 | 0.88 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL7024172 | 0.88 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL28427879 | 0.87 | GRIK1 (0.36) | GRIK1GRIK2 | |
| SCHEMBL18941015 | 0.85 | GRIK1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL28456126 | 0.78 | — | — | |
| SCHEMBL28427878 | 0.75 | GRIK1 (0.36) | GRIK1GRIK2 | |
| SCHEMBL28436247 | 0.75 | HTR2A (0.45) | GRIK1GRIK2 | |
| SCHEMBL17274510 | 0.72 | GRIK1 (0.32) | GRIK1GRIK2 | |
| SCHEMBL28427874 | 0.72 | GRIK1 (0.32) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107802623-B | Difluorolactam compositions for EP 4-mediated bone-related diseases and disorders | 开曼化学股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-106748951-B | Difluorolactam compounds as EP4 receptor selective agonists for use in the treatment of EP4 mediated diseases and conditions | 开曼化学股份有限公司 | 2020-07-24 | — | — | CN | disclosed |
| EP-0789022-B1 | Difluoroprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-0669329-B1 | Difluorprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5747531-A | STABILITY; ANTICOAGULANTS, VASODILATORS | ASAHI GLASS COMPANY LTD. (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0789022-A1 | Difluoroprostacyclins, intermediates for production thereof and process for production | ASAHI GLASS COMPANY LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5616732-A | Intermediates for difluoroprostacyclins and methods for their production | ASAHI GLASS COMPANY LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5538995-A | Difluoroprostacyclins | ASAHI GLASS COMPANY LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0669329-A1 | Difluorprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS COMPANY LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |