SCHEMBL7024410

SCHEMBL7024410

CC(C)=C1[C]=C(C2c3ccccc3-c3ccccc32)C=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
GPR3 P46089 2/20 0.34
HTR2A P28223 1/20 0.34
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
ACHE P22303 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
KMT2A Q03164 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455248 0.83 POLB (0.33) POLBGPR3HTR2A
SCHEMBL7592004 0.79 HTR2A (0.32) HTR2A
SCHEMBL7030170 0.71 POLB (0.34) POLBGPR3HTR2A
SCHEMBL9019442 0.70
SCHEMBL7595432 0.68 PTPN1 (0.33) POLBKMT2A
SCHEMBL9019415 0.66 HTR2A (0.32) HTR2AACHE
SCHEMBL27510570 0.63 POLB (0.36) POLBGPR3HTR2AKMT2AHDAC3
SCHEMBL8366223 0.62 POLB (0.35) POLBGPR3HTR2A
SCHEMBL27885617 0.61 HTR2A (0.52) POLBGPR3HTR2ACHRM2HTR1A
SCHEMBL25214731 0.61 HDAC3 (0.50) POLBGPR3HTR2ACHRM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889059-B1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 2003-02-12 EP disclosed
US-6388032-B1 SEPARATION BY FILTRATION TEIJIN LIMITED (JP) 2002-05-14 US disclosed
EP-1028128-A1 CYCLOOLEFIN POLYMER REDUCED IN CATALYST RESIDUE CONTENT, USE THEREOF, AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2000-08-16 EP disclosed
US-5965678-A Catalyst system based on monoazadiene metal complexes BAYER AG (DE) 1999-10-12 US disclosed
EP-0891382-A1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LIMITED (JP) 1999-01-20 EP disclosed
EP-0889059-A1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 1999-01-07 EP disclosed
WO-1998033830-A1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LIMITED (JP) 1998-08-06 WO disclosed
EP-0387690-A1 Process for preparing a syndiotactic polyolefin HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-19 EP disclosed