Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024828 | 0.86 | KCNH2 (0.44) | KCNH2TSHRKCNJ1IDO1KDM4E | |
| SCHEMBL14247542 | 0.85 | IDO1 (0.50) | TSHRIDO1LOXL2ALDH1A1LMNA | |
| SCHEMBL22801204 | 0.79 | CYP1A2 (0.38) | KCNH2IDO1ALDH1A1MAPT | |
| SCHEMBL12202764 | 0.79 | TSHR (0.53) | KCNH2TSHRKCNJ1IDO1LOXL2 | |
| SCHEMBL6753829 | 0.78 | KCNH2 (0.49) | KCNH2TSHRKCNJ1IDO1LOXL2 | |
| SCHEMBL22801232 | 0.77 | TAAR1 (0.42) | KDM4EMAPT | |
| SCHEMBL21178001 | 0.77 | CA1 (0.41) | IDO1 | |
| SCHEMBL7805282 | 0.75 | TSHR (0.58) | KCNH2TSHRKCNJ1IDO1LOXL2 | |
| Hydrochloric Acid SCHEMBL9772287 | 0.74 | TSHR (0.56) | KCNH2TSHRKCNJ1IDO1LOXL2 | |
| SCHEMBL4985770 | 0.73 | TSHR (0.58) | KCNH2TSHRKCNJ1IDO1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777485-B1 | 2',5' PHOSPHOROTHIOATE/PHOSPHODIESTER OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | UNIV TEMPLE (US) | 2003-02-19 | — | — | EP | disclosed |
| EP-0818460-B1 | Synthesis of Oligonucleotides on a solid support. | AVENTIS PHARMA GMBH (DE) | 2003-01-15 | — | — | EP | disclosed |
| US-5936077-A | PROTECTING EXOCYCLIC AMINO GROUPS OF NUCLEOTIDE WITH A CYCLIC DIACYL GROUP; COUPLING NUCLEOTIDE TO SOLID SUPPORT; SEQUENTIALLY LINKING NUCLEOTIDES TOGETHER; DEPROTECTING WITH STRONG, NONNUCLEOPHILIC BASE IN ORGANIC SOLVENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | disclosed |
| US-5866700-A | Solid-phase synthesis of oligoribonucleotides | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |
| EP-0777485-A4 | 2',5' PHOSPHOROTHIOATE/PHOSPHODIESTER OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | UNIV TEMPLE (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0818460-A2 | Synthesis of Oligonucleotides on a solid support. | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-14 | — | — | EP | disclosed |
| US-5652358-A | Solid-phase synthesis of oligoribonucleotides | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| US-5643889-A | Cholesterol conjugates of 2'5'-oligoadenylate derivatives and antiviral uses thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF PENNSYLVANIA (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0777485-A1 | 2',5' PHOSPHOROTHIOATE/PHOSPHODIESTER OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | Temple University of the Commonwealth System of Higher Education (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996008256-A1 | 2',5' PHOSPHOROTHIOATE/PHOSPHODIESTER OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1996-03-21 | — | — | WO | disclosed |