Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385887 | 1.00 | TLR4 (0.32) | TLR4 | |
| SCHEMBL8390649 | 0.92 | CYP1A2 (0.33) | — | |
| SCHEMBL7023040 | 0.92 | CYP1A2 (0.33) | — | |
| SCHEMBL8386994 | 0.92 | — | — | |
| SCHEMBL7030991 | 0.92 | — | — | |
| SCHEMBL7025199 | 0.91 | MEN1 (0.31) | — | |
| SCHEMBL8390641 | 0.91 | MEN1 (0.31) | — | |
| SCHEMBL7025806 | 0.88 | — | — | |
| SCHEMBL8385701 | 0.88 | — | — | |
| SCHEMBL8389689 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| US-5888423-A | Fluorobenzyl ether derivatives | ROLIC AG (CH) | 1999-03-30 | — | — | US | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |