SCHEMBL7024902

SCHEMBL7024902

C=C(C)C(=O)OCCc1cc(Cc2cc(C(C)(C)CCCCC)cc(-n3nc4ccccc4n3)c2O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 10/20 0.34
CNR1 P21554 10/20 0.34
GPR55 Q9Y2T6 4/20 0.34
GPR18 Q14330 3/20 0.34
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226073 0.92 TSHR (0.35) CNR2CNR1GPR55GPR18TSHR
SCHEMBL7030305 0.91 NPC1 (0.31)
SCHEMBL7023514 0.89 TSHR (0.37) CNR2CNR1TSHR
SCHEMBL7026741 0.88 NPC1 (0.32)
SCHEMBL7027240 0.88 TSHR (0.39) CNR2CNR1TSHR
SCHEMBL7031681 0.88 TSHR (0.35) TSHR
SCHEMBL7026527 0.86 NPC1 (0.34) TSHR
SCHEMBL7736250 0.86 NPC1 (0.37)
SCHEMBL7029552 0.85 NPC1 (0.31)
SCHEMBL7030431 0.85 NPC1 (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924203-B1 2,2'-BIS(6-BENZOTRIAZOLYLPHENOL) COMPOUNDS, ULTRAVIOLET ABSORBERS COMPRISING THE SAME, COPOLYMERS CONTAINING THE SAME, AND POLYMER COMPOSITIONS CONTAINING THE SAME OTSUKA CHEMICAL CO LTD (JP) 2003-02-05 EP disclosed
US-6281313-B1 2,2′BIS(6-Benzotriazolylphenol) compound, ultraviolet ray absorber comprising the compound, copolymer containing the compound and polymer composition containing the compound OTSUKA CHEMICAL CO., LTD. (JP) 2001-08-28 US disclosed
US-6084104-A FREE FROM VOLATILITY AND ELUTION PROBLEMS DURING POLYMERIZATION OR MOLDING; EXCELLENT IN ALKALI RESISTANCE, HEAT RESISTANCE; NOT COLORED WHERE ALKALIS OR METAL IONS ARE PRESENT; EXCELLENT ULTRAVIOLET ABSORPTIVITY; WEATHERING OTSUKA CHEMICAL CO., LTD. (JP) 2000-07-04 US disclosed
EP-0924203-A1 2,2'-BIS(6-BENZOTRIAZOLYLPHENOL) COMPOUNDS, ULTRAVIOLET ABSORBERS COMPRISING THE SAME, COPOLYMERS CONTAINING THE SAME, AND POLYMER COMPOSITIONS CONTAINING THE SAME OTSUKA CHEMICAL COMPANY, LIMITED (JP) 1999-06-23 EP disclosed