SCHEMBL7025925

SCHEMBL7025925

CCOC(=O)C1CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28229158 0.88 PPM1B (0.42)
SCHEMBL1470851 0.86 DPP4 (0.37)
SCHEMBL6884033 0.86 KDM4E (0.36)
SCHEMBL3316703 0.86 DPP4 (0.37)
SCHEMBL9684605 0.86 DPP4 (0.37)
SCHEMBL1567974 0.86 DPP4 (0.37)
SCHEMBL9637120 0.86 KDM4E (0.36)
SCHEMBL4892915 0.86 DPP4 (0.37)
SCHEMBL22897291 0.86 KDM4E (0.36)
SCHEMBL2389792 0.86 DPP4 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117500811-A Covalent RAS inhibitors and uses thereof 锐新医药公司 2024-02-02 CN disclosed
CN-115916194-A Methods for delaying, preventing and treating acquired resistance to RAS inhibitors 锐新医药公司 2023-04-04 CN disclosed
CN-114729044-A Muscarinic acetylcholine M1Receptor antagonists 帕珀莱恩医疗公司 2022-07-08 CN disclosed
WO-2008046232-A1 AZIRIDINE ALDEHYDES, AZIRIDINE-CONJUGATED AMINO DERIVATIVES, AZIRIDINE-CONJUGATED BIOMOLECULES AND PROCESSES FOR THEIR PREPARATION YUDIN ANDREI K (CA) 2008-04-24 WO disclosed
US-20030129222-A1 Administering to a cancer patient a therapeutically effective amount of imexon or derivative in combination with one or more lipids to treat the cancer VALLEY VENTURES III, L.P. 2003-07-10 US disclosed
WO-2002041871-A9 COMPOSITION COMPRISING AN IMEXON OR DERIVATIVES THEREOF AND LIPIDS UNIV TEXAS (US) 2003-05-30 WO disclosed
WO-2002041871-A2 COMPOSITION COMPRISING AN IMEXON OR DERIVATIVES THEREOF AND LIPIDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2002-05-30 WO disclosed
US-6297230-B1 N-CARBAMOYL-SUBSTITUTED AMPLIMED, INC. 2001-10-02 US disclosed
EP-1027041-A4 NOVEL CYANOAZIRIDINES FOR TREATING CANCER UNIV ARIZONA (US) 2001-06-13 EP disclosed
EP-1027041-A1 NOVEL CYANOAZIRIDINES FOR TREATING CANCER THE ARIZONA BOARD OF REGENTS, ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2000-08-16 EP disclosed
WO-1993014082-A1 PYRIDYL SUBSTITUTED IMIDAZOLES SMITHKLINE BEECHAM CORPORATION (US) 1993-07-22 WO disclosed
US-4935527-A SEPARATION FROM IMPURITIES BY ION EXCHANGING ON A CATIONIC EXCHANGER BED RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1990-06-19 US disclosed
EP-0191462-A1 Purification of aziridine-2-carboxylic acid salts RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1986-08-20 EP disclosed
EP-0030870-B1 PROCESS FOR PRODUCING SOLUTIONS OF AZIRIDINE-2-CARBOXYLIC ACID SALT MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-03-20 EP disclosed
EP-0030475-B1 PROCESS FOR PRODUCING SOLUTIONS OF AZIRIDINE-2-CARBOXYLIC ACID SALTS MITSUI TOATSU CHEMICALS, Inc. (JP) 1984-03-14 EP disclosed
US-4393000-A DEHYDROHALOGENATION OF ALPHA-HALO-BETA-AMINOPROPIONITRILE MITSUI TOATSU CHEMICALS, INC. (JP) 1983-07-12 US disclosed
EP-0030474-B1 PROCESS FOR THE PRODUCTION OF DL-SERINES MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-01-19 EP disclosed
US-4304933-A HEATING AZIRIDINE-2-CARBOXYLIC ACID ON ION EXCHANGE RESIN MITSUI TOATSU CHEMICALS, INC. (JP) 1981-12-08 US disclosed
EP-0030474-A1 Process for the production of DL-serines MITSUI TOATSU CHEMICALS, Inc. (JP) 1981-06-17 EP disclosed
EP-0030475-A1 Process for producing solutions of aziridine-2-carboxylic acid salts MITSUI TOATSU CHEMICALS, Inc. (JP) 1981-06-17 EP disclosed