Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779792 | 0.84 | PNP (0.58) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL20567028 | 0.83 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL3744956 | 0.81 | PNP (0.60) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL6535098 | 0.81 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL3425761 | 0.81 | PNP (0.57) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL6561796 | 0.80 | PNP (0.53) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23647921 | 0.79 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17521212 | 0.79 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL3707304 | 0.79 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7199411 | 0.79 | PNP (0.62) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818460-B1 | Synthesis of Oligonucleotides on a solid support. | AVENTIS PHARMA GMBH (DE) | 2003-01-15 | — | — | EP | disclosed |
| EP-0818460-A2 | Synthesis of Oligonucleotides on a solid support. | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-14 | — | — | EP | disclosed |