Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028151 | 1.00 | TDP1 (0.48) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL12738779 | 1.00 | TDP1 (0.48) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL7022280 | 1.00 | TDP1 (0.48) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL7022285 | 1.00 | TDP1 (0.48) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL7017483 | 1.00 | TDP1 (0.48) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL21055708 | 0.87 | CYP1A2 (0.49) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL21055707 | 0.87 | CYP1A2 (0.49) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL7194535 | 0.87 | CYP1A2 (0.49) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL7097856 | 0.85 | TDP1 (0.52) | TDP1GLACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL1199677 | 0.85 | TDP1 (0.52) | TDP1GLACYP1A2ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872467-B1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEM CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-5886214-A | CATALYTIC ASYMMETRIC HYDROGENATION OF ENOL ESTERS BEARING A VINYLLIC OR AN ACETYLENIC SUBSTITUENT BY USING A CHIRAL RHODIUM(I) HYDROGENATION CATALYST PREPARED FROM A SUITABLE RHODIUM SALT AND AN OPTICALLY PURE PHOSPHINE LIGAND | EASTMAN CHEMICAL COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0872467-A1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEMICAL COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |