Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028364 | 0.97 | GCGR (0.34) | ESR2GCGRRARBRARARARG | |
| SCHEMBL7027934 | 0.93 | FASN (0.32) | — | |
| SCHEMBL7028220 | 0.88 | ESR2 (0.35) | ESR2RARBRARARARGPPARA | |
| SCHEMBL9764101 | 0.86 | ESR2 (0.34) | ESR2RARBRARARARG | |
| SCHEMBL19844676 | 0.84 | ESR2 (0.34) | ESR2PPARA | |
| SCHEMBL7027472 | 0.84 | RARB (0.35) | ESR2GCGRRARBRARARARG | |
| SCHEMBL7026189 | 0.84 | ESR2 (0.33) | ESR2 | |
| SCHEMBL13615107 | 0.84 | RARB (0.30) | ESR2RARBRARARARG | |
| SCHEMBL7026162 | 0.83 | — | — | |
| SCHEMBL9764316 | 0.82 | RARB (0.32) | ESR2RARBRARARARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |