Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7018692 | 0.99 | F2 (0.45) | F2PRSS1KAT2BPRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7020182 | 0.99 | F2 (0.45) | F2PRSS1KAT2BPRSS2PRSS3 | |
| SCHEMBL8293357 | 0.89 | F2 (0.41) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8490818 | 0.88 | F2 (0.36) | F2KAT2B | |
| SCHEMBL7025837 | 0.87 | F2 (0.41) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8292991 | 0.87 | F2 (0.38) | F2KAT2B | |
| Hydrochloric Acid SCHEMBL7027725 | 0.86 | F2 (0.40) | F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7026964 | 0.85 | F2 (0.39) | F2PRSS1KAT2BPRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7017874 | 0.82 | F2 (0.41) | F2PRSS1KAT2B | |
| Hydrochloric Acid SCHEMBL7022590 | 0.81 | F2 (0.41) | F2PRSS1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |