Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7030534 | 0.99 | CACNA1C (0.78) | CACNA1CMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29447128 | 0.89 | CACNA1C (1.00) | CACNA1CMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL742344 | 0.89 | CACNA1C (1.00) | CACNA1CMAPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7028351 | 0.88 | CACNA1C (0.98) | CACNA1CMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12389509 | 0.88 | CACNA1C (0.76) | CACNA1CMAPTALDH1A1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7022421 | 0.86 | CACNA1C (0.73) | CACNA1CMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7027453 | 0.84 | CACNA1C (0.71) | CACNA1CMAPTALDH1A1GAASLC6A4 | |
| Hydrochloric Acid SCHEMBL7028292 | 0.83 | CACNA1C (0.70) | CACNA1CMAPTGAASLC6A4HTR2A | |
| SCHEMBL13577199 | 0.80 | CACNA1C (0.62) | CACNA1CMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7022579 | 0.80 | CACNA1C (0.52) | CACNA1CMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031556-B1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6162832-A | 2-Phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO., INC. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-1031556-A1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-08-30 | — | — | EP | disclosed |