Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031978 | 0.93 | POLA1 (0.59) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6698535 | 0.92 | POLA1 (0.53) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6699326 | 0.89 | POLA1 (0.52) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6696093 | 0.88 | POLA1 (0.51) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6697411 | 0.88 | POLA1 (0.54) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6699084 | 0.88 | POLA1 (0.51) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6698378 | 0.87 | POLA1 (0.50) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6693371 | 0.85 | POLA1 (0.64) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6699282 | 0.85 | POLA1 (0.54) | POLA1KCNH2RXFP1ENPP2ALDH1A1 | |
| SCHEMBL6697957 | 0.85 | POLA1 (0.53) | POLA1KCNH2RXFP1ENPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299395-B1 | OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS | UPJOHN CO (US) | 2004-09-15 | — | — | EP | claimed |