Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 9/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027613 | 1.00 | FOLH1 (0.46) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL3725106 | 1.00 | FOLH1 (0.46) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL209237 | 0.94 | FOLH1 (0.53) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL1413149 | 0.94 | FOLH1 (0.53) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL3727817 | 0.94 | FOLH1 (0.53) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL8191952 | 0.88 | GABRR1 (0.52) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL756912 | 0.88 | GABRR1 (0.52) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL8254457 | 0.86 | FOLH1 (0.45) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL4783069 | 0.86 | FOLH1 (0.45) | FOLH1GABRR1CPB2GSRRNPEP | |
| SCHEMBL4783065 | 0.86 | FOLH1 (0.45) | FOLH1GABRR1CPB2GSRRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822827-B1 | ANTAGONISTS OF LHRH | UNIV TEXAS (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-0804471-A1 | GNRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5506207-A | CONTRACEPTIVES, ANTITUMOR AGENTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-04-09 | — | — | US | disclosed |
| WO-1995025741-A1 | GNRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1995-09-28 | — | — | WO | disclosed |
| EP-0377665-B1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE | UNIV TEXAS (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0536203-B1 | COMBINED TREATMENT WITH GnRH ANTAGONIST AND GnRH TO CONTROL GONADOTROPIN LEVELS IN MAMMALS | APPLIED RESEARCH SYSTEMS (AN) | 1995-02-08 | — | — | EP | disclosed |
| WO-1994019370-A1 | GNRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-09-01 | — | — | WO | disclosed |
| WO-1991019743-A2 | COMBINED TREATMENT WITH GnRH ANTAGONIST AND GnRH TO CONTROL GONADOTROPIN LEVELS IN MAMMALS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1991-12-26 | — | — | WO | disclosed |
| EP-0377665-A1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE. | UNIV TEXAS (US) | 1990-07-18 | — | — | EP | disclosed |
| WO-1989009786-A1 | PEPTIDE DERIVATIVES | SANDOZ AG (CH) | 1989-10-19 | — | — | WO | disclosed |
| WO-1989001944-A1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1989-03-09 | — | — | WO | disclosed |