SCHEMBL702844

SCHEMBL702844

CCOC(=O)COc1c(C(=O)N[C@H](C)c2ccc(C(F)(F)F)cc2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.67
CNR2 P34972 4/20 0.67
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL708712 0.91 CNR1 (0.70) CNR1CNR2
SCHEMBL6123512 0.90 CNR1 (0.69) CNR1CNR2
SCHEMBL10087194 0.87 CNR1 (0.68) CNR1CNR2
SCHEMBL10087243 0.87 CNR1 (0.67) CNR1CNR2
SCHEMBL10087193 0.85 CNR1 (0.82) CNR1CNR2
SCHEMBL706792 0.83 CNR1 (0.68) CNR1CNR2
SCHEMBL10087161 0.83 CNR1 (0.69) CNR1CNR2
SCHEMBL702992 0.82 CNR1 (0.73) CNR1CNR2
SCHEMBL6123693 0.82 CNR1 (0.73) CNR1CNR2
SCHEMBL6123663 0.82 CNR1 (0.72) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121617-B1 CB1 RECEPTOR MODULATORS 7TM PHARMA AS (DK) 2014-01-22 EP disclosed
US-8124634-B2 CB1 receptor modulators 7TM PHARMA A/S (DK) 2012-02-28 US disclosed
US-20100010061-A1 CB1 RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2010-01-14 US disclosed
EP-2121617-A1 CB1 RECEPTOR MODULATORS 7TM Pharma A/S (DK) 2009-11-25 EP disclosed
WO-2008075012-A1 CB1 RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2008-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100010061-A1 CB1 RECEPTOR MODULATORS CNR1, CNR2, GPR6 CNR1 1/4885CNR2 2/4885MAPT 4450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.