Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | BID | P55957 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118770 | 0.85 | PPARA (0.49) | PPARAPPARGSCN1ASCN2ASCN3A | |
| SCHEMBL5693545 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL5520861 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL5525480 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL5525483 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL5516277 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL5516982 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL5521143 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL1682784 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 | |
| SCHEMBL1682785 | 0.80 | BID (0.51) | PPARAPPARGBIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973811-B1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING SA (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6476103-B1 | Photochromic organic material, its manufacture and the photochromic articles containing it | CORNING INCORPORATED | 2002-11-05 | — | — | US | disclosed |
| EP-0973811-A4 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING SA (FR) | 2000-07-12 | — | — | EP | disclosed |
| EP-0973811-A1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING INCORPORATED (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0931278-A4 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0931278-A1 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INCORPORATED (US) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998045341-A1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING INCORPORATED (US) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998016863-A1 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INCORPORATED (US) | 1998-04-23 | — | — | WO | disclosed |