Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029525 | 0.93 | HTR2A (0.34) | HTR2AHTR2C | |
| SCHEMBL7028454 | 0.91 | HTR2A (0.35) | HTR2AHTR2CNPC1GPR84 | |
| SCHEMBL7025226 | 0.90 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL9256823 | 0.85 | SLC6A2 (0.35) | NPC1GPR84 | |
| SCHEMBL9256837 | 0.85 | SLC6A2 (0.35) | NPC1GPR84 | |
| SCHEMBL9256842 | 0.85 | SLC6A2 (0.35) | NPC1GPR84 | |
| SCHEMBL7034717 | 0.85 | ESR2 (0.38) | HTR2AHTR2C | |
| SCHEMBL7029159 | 0.84 | NPC1 (0.30) | NPC1 | |
| SCHEMBL7031261 | 0.84 | HTR2A (0.37) | HTR2AHTR2CNPC1GPR84 | |
| SCHEMBL7025178 | 0.84 | HTR2A (0.37) | HTR2AHTR2CNPC1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |