⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436290 | 1.00 | — | — | |
| SCHEMBL254616 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29446951 | 0.97 | — | — | |
| SCHEMBL10723948 | 0.79 | — | — | |
| SCHEMBL12380265 | 0.76 | — | — | |
| SCHEMBL15074981 | 0.73 | — | — | |
| SCHEMBL1570079 | 0.73 | — | — | |
| SCHEMBL7680338 | 0.73 | — | — | |
| SCHEMBL2777562 | 0.73 | — | — | |
| SCHEMBL16566045 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102070473-B | Method for synthesizing D-valine | Shanghai yaben chemistry co ltd | 2013-10-16 | — | — | CN | claimed |
| EP-3228325-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Mersana Therapeutics, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| US-9102708-B2 | Methods for the synthesis of dicarba bridges in organic compounds | SYNGENE LIMITED (AU) | 2015-08-11 | — | — | US | disclosed |
| EP-2536730-B1 | PYRROLOPYRIMIDINE COMPOUNDS AS INHIBITORS OF CDK4/6 | NOVARTIS AG (CH) | 2015-07-08 | — | — | EP | disclosed |
| WO-2015034920-A2 | GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR COMPOSITIONS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-03-12 | — | — | WO | disclosed |
| CN-104350042-A | Neprilysin inhibitors | THERAVANCE BIOPHARMA R & D IP LLC | 2015-02-11 | — | — | CN | disclosed |
| US-8846624-B2 | Modified protein polymers | EMORY UNIVERSITY (US) | 2014-09-30 | — | — | US | disclosed |
| US-8575094-B2 | Use of type-B lantibiotic-based compounds having antimicrobial activity | NOVACTA BIOSYSTEMS LIMITED (GB) | 2013-11-05 | — | — | US | disclosed |
| US-8357638-B2 | Oligonucleotide library encoding randomised peptides | ASTON UNIVERSITY (GB) | 2013-01-22 | — | — | US | disclosed |
| US-8329644-B2 | Lantibiotic-based compounds having antimicrobial activity | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-12-11 | — | — | US | disclosed |
| US-20100036089-A1 | Methods for the Synthesis of Dicarba Bridges in Organic Compounds | MONASH UNIVERSITY (AU) | 2010-02-11 | — | — | US | disclosed |
| US-20100022749-A1 | Contoxin Analogues and Methods for Synthesizing Same | MONASH UNIVERSITY (AU) | 2010-01-28 | — | — | US | disclosed |
| US-7632807-B2 | Cyclosporin alkynes and their utility as pharmaceutical agents | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-20090264313-A1 | Oligonucleotide library encoding randomised peptides | ASTON UNIVERSITY (GB) | 2009-10-22 | — | — | US | disclosed |
| US-20090203583-A1 | Use of Type-B Lantibiotic-Based Compounds having Antimicrobial Activity | NOVACTA BIOSYSTEMS LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20080153744-A1 | NOVEL CYCLOSPORIN ALKYNES AND THEIR UTILITY AS PHARMACEUTICAL AGENTS | AMR TECHNOLOGY, INC. (US) | 2008-06-26 | — | — | US | disclosed |
| US-7358229-B2 | Deuterated cyclosporin analogs and their use as immunomodulating agents | ISOTECHNIKA INC. (CA) | 2008-04-15 | — | — | US | disclosed |
| US-7307148-B2 | Method for purification of albumin conjugates | CONJUCHEM BIOTECHNOLOGIES INC. (CA) | 2007-12-11 | — | — | US | disclosed |
| US-20070280939-A1 | Prostatic Acid Phosphatase Antigens | NOTTINGHAM TRENT UNIVERSITY, THE (GB) | 2007-12-06 | — | — | US | disclosed |
| US-20070243562-A1 | Lectins for Analyzing Sugar Chains and Method of Using the Same | SUMMIT GLYCORESEARCH CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |