Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449006 | 0.83 | KDM4E (0.47) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL4402348 | 0.83 | KDM4E (0.47) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL4967419 | 0.82 | KDM4E (0.41) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL472764 | 0.82 | KDM4E (0.41) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL5718788 | 0.82 | KDM4E (0.41) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL4967632 | 0.82 | KDM4E (0.41) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL301572 | 0.80 | KDM4E (0.40) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL7032966 | 0.80 | KDM4E (0.40) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL13791007 | 0.80 | KDM4E (0.40) | KDM4ELMNAEPHX2ALDH1A1GAA | |
| SCHEMBL1299179 | 0.80 | KDM4E (0.40) | KDM4ELMNAEPHX2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190244-B1 | METHOD OF PRODUCING MONOLITHIC SUPPORT MATERIALS | BUCHMEISER MICHAEL RUDOLF (AT) | 2003-02-26 | — | — | EP | disclosed |
| EP-1190244-A1 | METHOD OF PRODUCING MONOLITHIC SUPPORT MATERIALS | MERCK PATENT GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000073782-A1 | METHOD OF PRODUCING MONOLITHIC SUPPORT MATERIALS | MERCK PATENT GMBH (DE) | 2000-12-07 | — | — | WO | disclosed |